王强

王强，男，博士，二级教授，博士生导师。于2002年在中国科学院北京植物研究所获得博士学位。2002年10月至2010年7月期间先后在以色列希伯来大学、美国田纳西大学、阿肯色大学和密西根州立大学从事独立研究工作。2011年获中国科学院“百人计划”择优资助。2019年1月入选河南大学“杰出人才特区支持计划”特聘教授。主持或参加国家“973”、国家重点研发计划、国家自然科学基金、省级自然科学基金重点和创新群体、以及中科院和所级创新领域前沿项目共十余项。近年来在Cell、Nat Plants、Plant Cell、Nat Commun、Mol Plant、New Phyto、Mol Microbiol、J Hazard Mat、EST、Biotechnol Biofuels、Appl Energ和AEM 等发表SCI 论文60余篇，应Springer Nature 邀请编著光合微生物学专著Microbial Photosynthesis。

研究方向：藻类生物学、光合作用环境胁迫响应与合成生物学。

以光合作用研究模式材料蓝细菌和小球藻为研究对象，立足光合作用与合成生物学，聚焦环境问题，围绕微藻环境适应、生物能源与生物减排等科学问题，开展系统性研究。

Email：wangqiang@henu.edu.cn

代表性研究论文：

1. Zheng, S., A. Wu, H. Wang, L. Chen, J. Song, H. Zhang, M. He, C. Wang, H. Chen, and Q. Wang, Purification efficiency of Pyropia-processing wastewater and microalgal biomass production by the combination of Chlorella sp. C2 cultivated at different culture temperatures and chitosan. Bioresource Technology, 2023: p. 128730.

2. Zheng Y, Xue C, Chen H, Jia A, Zhao L, Zhang J, Zhang L, Wang Q. Reconstitution and expression of mcy gene cluster in the model cyanobacterium Synechococcus 7942 reveals a role of MC-LR in cell division. New Phytol. 2023 Jan 23. doi: 10.1111/nph.18766. Epub ahead of print. PMID: 36683448.

3. Zheng, S., S. Chen, A. Wu, H. Wang, S. Sun, M. He, C. Wang, H. Chen, and Q. Wang, Efficient nutrient removal of Pyropia-processing wastewater and rapid algal biomass harvesting by Scenedesmus obliquus combined with chitosan. Journal of Water Process Engineering, 2023. 51: p. 103365.

4. Sun, Z., H. Chen, L. Sun, and Q. Wang, Converting carbon dioxide to high value-added products: Microalgae-based green biomanufacturing. GCB Bioenergy, 2023;15:386-398.

5. Hu, X., Y. Fan, C. Mao, H. Chen, and Q. Wang, Application of transposon insertion site sequencing method in the exploration of gene function in microalgae. Frontiers in Microbiology, 2023. 14.

6. Hu, J., D. Wang, H. Chen, and Q. Wang, Advances in Genetic Engineering in Improving Photosynthesis and Microalgal Productivity. International Journal of Molecular Sciences, 2023. 24(3): p. 1898.

7. Chen, W., T. Li, Y. Ren, J. Wang, H. Chen, and Q. Wang, Biological hydrogen with industrial potential: Improvement and prospection in biohydrogen production. Journal of Cleaner Production, 2023. 387: p. 135777.

8. 孙中亮，史良，王强, 刘., 黄河流域微塑料污染现状及防治策略. 生物工程学报, 2023: p. 1-14.

9. Zheng, S., S. Zou, H. Wang, T. Feng, S. Sun, H. Chen, and Q. Wang, Reducing culture medium nitrogen supply coupled with replenishing carbon nutrient simultaneously enhances the biomass and lipid production of Chlamydomonas reinhardtii. Frontiers in Microbiology, 2022. 13.

10. Zheng, S., S. Zou, T. Feng, S. Sun, X. Guo, M. He, C. Wang, H. Chen, and Q. Wang, Low temperature combined with high inoculum density improves alpha-linolenic acid production and biochemical characteristics of Chlamydomonas reinhardtii. Bioresour Technol, 2022. 348: p. 126746.

11. Li, X., C. Xue, H. Chen, H. Zhang, and Q. Wang, Small antisense RNA ThfR positively regulates Thf1 in Synechocystis sp. PCC 6803. Journal of Plant Physiology, 2022. 271: p. 153642.

12. Dai, N., Q. Wang, B. Xu, and H. Chen, Remarkable Natural Biological Resource of Algae for Medical Applications. Frontiers in Marine Science, 2022. 9.

13. Chen, H. and Q. Wang, Microalgae-Based Green Bio-Manufacturing—How Far From Us. Frontiers in Microbiology, 2022. 13.

14. 孙中亮, 陈辉, 王强, 从CO2到有机物—碳中和的微藻绿色生物制造. 合成生物学, 2022: p. 1-13.

15. Chen H., Li K., Xue C., Wang Q. A Novel Method for Non-invasive Estimation of Primary Productivity in Aquatic Ecosystems Using a Chlorophyll Fluorescence-Induced Dynamic Curve [J]. Frontiers in Microbiology, 2021, 12: 682250.

16. Chen H., Wang Q. Regulatory mechanisms of lipid biosynthesis in microalgae [J]. Biological Reviews, 2021, 96(5): 2373-2391.

17. Chen H., Wang Q. Microalgae-Based Green Bio-Manufacturing-How Far From Us [J]. Journal, 2022, 13(Issue): 832097.

18. Jia A., Zheng Y., Chen H., Wang Q. Regulation and Functional Complexity of the Chlorophyll-Binding Protein IsiA [J]. Frontiers in Microbiology, 2021, 12: 774107-774107.

19. Li X., Xue C., Chen H., Zhang H., Wang Q. Small antisense RNA ThfR positively regulates Thf1 in Synechocystis sp. PCC 6803 [J]. Journal of Plant Physiology, 2022, 271: 153642.

20. Zheng Y., Xue C., Chen H., He C., Wang Q. Low-temperature adaptation of the snow alga Chlamydomonas nivalis is associated with the photosynthetic system regulatory process [J]. Frontiers in Microbiology, 2020, 11: 1233.

21. Zhou C., Chen H., Zhao H., Wang Q. Microcystin biosynthesis and toxic effects [J]. Algal Research-Biomass Biofuels and Bioproducts, 2021, 55: 102277.

22. Li, T., Jiang, Q., Huang, J., Aitchison, C.M., Huang, F., Yang, M., Dykes, G.F., He, H.L., Wang, Q., Sprick, R.S. Reprogramming bacterial protein organelles as a nanoreactor for hydrogen production. Nature Communications, 2020, 11:5448.

23. Zhao, L.-S., Huokko, T., Wilson, S., Simpson, D.M., Wang, Q., Ruban, A.V., Mullineaux, C.W., Zhang, Y.-Z., Liu, L.-N. Structural variability, coordination and adaptation of a native photosynthetic machinery. Nature Plants, 2020, 6(7): 869-882.

24. Zheng, S., Chen, S., Zou, S., Yan, Y., Gao, G., He, M., Wang, C., Chen, H., Wang, Q. Bioremediation of Pyropia-processing wastewater coupled with lipid production using Chlorella sp. Bioresource Technology, 2021, 321.

25. Zhang, X., Chen, H., Wang, H., Wang, Q. Time-course effects of Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) on Chlorella pyrenoidosa: Growth inhibition and adaptability mechanisms. Journal of Hazardous Materials, 2021, 402: 123784.

26. Wang Q. Microbial Photosynthesis, Springer Nature, 2020；

27. Chen, H., Wang, X., and Wang, Q. Microalgal biofuels in China: The past, progress and prospects. Global Change Biology Bioenergy. 2020, 12: 1044-1065;

28. Chen, H., and Wang, Q. Microalgae-based nitrogen bioremediation. Algal Research 2020, 46:101775;

29. Calzadilla, P.I., Zhan, J., Sétif, P., Lemaire, C., Solymosi, D., Battchikova, N., Wang, Q., and Kirilovsky, D. The cytochrome b6f complex is not involved in cyanobacterial state transitions. The Plant Cell, 2019, 31, 911-931;

30. Wang J, Zhou W, Chen H, Zhan J, He C and Wang Q. Ammonium Nitrogen Tolerant Chlorella Strain Screening and Its Damaging Effects on Photosynthesis. Front. Microbiol. 2019, 9:3250. doi: 10.3389/fmicb.2018.03250

31. Chen, H., Li, T., and Wang, Q. Ten years of algal biofuel and bioproducts: gains and pains. Planta, 2019, 249:195-219；

32. Zhan, J., and Wang, Q. Photoresponse Mechanism in Cyanobacteria: Key Factor in Photoautotrophic Chassis, in Synthetic Biology of Cyanobacteria, eds. W. Zhang & X. Song. (Singapore: Springer Singapore), 2018, 75-96.

33. Hu, J., Zhan, J., Chen, H., He, C., Cang, H., and Wang, Q. (2018). The Small Regulatory Antisense RNA PilR Affects Pilus Formation and Cell Motility by Negatively Regulating pilA11 in Synechocystis sp. PCC 6803. Frontiers in Microbiology, 2018, 9(786).

34. Hu, J., and Wang, Q. (2018). Regulatory sRNAs in Cyanobacteria. Frontiers in Microbiology, 2018, 9(2399).

35. Chen, H., and Wang, Q. Ten years of microalgal biofuels in environmental applications. Science Foundation in China 2018, 26(3), 69-80.

36. Giordano M, Wang Q. Microalgae for Industrial Purposes. In: Vaz Jr S, (ed). Biomass and Green Chemistry: Building a Renewable Pathway. Cham: Springer Nature Publishing, 2018, 133-167

37. Chen H, Wang J, Zheng Y, Zhan J, He C, Wang Q. Algal biofuel production coupled bioremediation of biomass power plant wastes based on Chlorella sp. C2 cultivation. Applied Energy, 2018, 211: 296-305

38. Zhang X, Ma F, Zhu X, Zhu J, Rong J, Zhan J, Chen H, He C, Wang Q. The Acceptor Side of Photosystem II Is the Initial Target of Nitrite Stress in Synechocystis sp. Strain PCC 6803. Appl Environ Microbiol, 2017, 83(3)

39. Zhan J, Rong J, Wang Q. Mixotrophic cultivation, a preferable microalgae cultivation mode for biomass/bioenergy production, and bioremediation, advances and prospect. International Journal of Hydrogen Energy, 2017, 42(12): 8505-8517

40. Ma F, Zhang X, Zhu X, Li T, Zhan J, Chen H, He C, Wang Q. Dynamic Changes of IsiA-Containing Complexes during Long-Term Iron Deficiency in Synechocystis sp. PCC 6803. Mol Plant, 2017, 10(1): 143-154

41. Hu J, Li T, Xu W, Zhan J, Chen H, He C, Wang Q. Small Antisense RNA RblR Positively Regulates RuBisCo in Synechocystis sp. PCC 6803. Front Microbiol, 2017, 8(231): 231

42. Chen H, Zhou W, Chen W, Xie W, Jiang L, Liang Q, Huang M, Wu Z, Wang Q. Simplified, rapid, and inexpensive estimation of water primary productivity based on chlorophyll fluorescence parameter Fo. J Plant Physiol, 2017, 211: 128-135

43. Chen H, Zheng Y, Zhan J, He C, Wang Q. Comparative metabolic profiling of the lipid-producing green microalga Chlorella reveals that nitrogen and carbon metabolic pathways contribute to lipid metabolism. Biotechnol Biofuels, 2017, 10(1): 153

44. Zhu X, Rong J, Chen H, He C, Hu W, Wang Q. An informatics-based analysis of developments to date and prospects for the application of microalgae in the biological sequestration of industrial flue gas. Appl Microbiol Biotechnol, 2016, 100(5): 2073-2082

45. Zhu J, Chen W, Chen H, Zhang X, He C, Rong J, Wang Q. Improved Productivity of Neutral Lipids in Chlorella sp. A2 by Minimal Nitrogen Supply. Front Microbiol, 2016, 7: 557

46. Zhan J, Zhu X, Zhou W, Chen H, He C, Wang Q. Thf1 interacts with PS I and stabilizes the PS I complex in Synechococcus sp. PCC7942. Mol Microbiol, 2016, 102(4): 738-751

47. Li T, Xu G, Rong J, Chen H, He C, Giordano M, Wang Q. The acclimation of Chlorella to high-level nitrite for potential application in biological NOx removal from industrial flue gases. J Plant Physiol, 2016, 195: 73-79

48. Chen W, Zhang S, Rong J, Li X, Chen H, He C, Wang Q. Effective Biological DeNOx of Industrial Flue Gas by the Mixotrophic Cultivation of an Oil-Producing Green Alga Chlorella sp. C2. Environ Sci Technol, 2016, 50(3): 1620-1627

49. Qiao Y, Rong J, Chen H, He C, Wang Q. Non-Invasive Rapid Harvest Time Determination of Oil-Producing Microalgae Cultivations for Biodiesel Production by Using Chlorophyll Fluorescence. Frontiers in Energy Research, 2015, 3

50. Mo R, Yang M, Chen Z, Cheng Z, Yi X, Li C, He C, Xiong Q, Chen H, Wang Q, Ge F. Acetylome analysis reveals the involvement of lysine acetylation in photosynthesis and carbon metabolism in the model cyanobacterium Synechocystis sp. PCC 6803. J Proteome Res, 2015, 14(2): 1275-1286

51. Daddy S, Zhan J, Jantaro S, He C, He Q, Wang Q. A novel high light-inducible carotenoid-binding protein complex in the thylakoid membranes of Synechocystis PCC 6803. Sci Rep, 2015, 5: 9480

52. Chen Z, Zhan J, Chen Y, Yang M, He C, Ge F, Wang Q. Effects of Phosphorylation of beta Subunits of Phycocyanins on State Transition in the Model Cyanobacterium Synechocystis sp. PCC 6803. Plant Cell Physiol, 2015, 56(10): 1997-2013

53. Chen H, Qiu T, Rong J F, He C L, Wang Q. Microalgal biofuel revisited: An informatics-based analysis of developments to date and future prospects. Applied Energy, 2015, 155: 585-598

54. Chen H, Hu J, Qiao Y, Chen W, Rong J, Zhang Y, He C, Wang Q. Ca(2+)-regulated cyclic electron flow supplies ATP for nitrogen starvation-induced lipid biosynthesis in green alga. Sci Rep, 2015, 5: 15117

55. Zhang X, Rong J, Chen H, He C, Wang Q. Current Status and Outlook in the Application of Microalgae in Biodiesel Production and Environmental Protection. Frontiers in Energy Research, 2014, 2

56. Zhang X, Chen H, Chen W, Qiao Y, He C, Wang Q. Evaluation of an oil-producing green alga Chlorella sp. C2 for biological DeNOx of industrial flue gases. Environ Sci Technol, 2014, 48(17): 10497-10504

57. Xu W, Chen H, He C L, Wang Q. Deep sequencing-based identification of small regulatory RNAs in Synechocystis sp. PCC 6803. PLoS One, 2014, 9(3): e92711

58. Chen H, Zhang Y, He C, Wang Q. Ca2+ signal transduction related to neutral lipid synthesis in an oil-producing green alga Chlorella sp. C2. Plant Cell Physiol, 2014, 55(3): 634-644

59. Chen G, Qu S, Wang Q, Bian F, Peng Z, Zhang Y, Ge H, Yu J, Xuan N, Bi Y, He Q. Transgenic expression of delta-6 and delta-15 fatty acid desaturases enhances omega-3 polyunsaturated fatty acid accumulation in Synechocystis sp. PCC6803. Biotechnol Biofuels, 2014, 7(1): 32

60. Zhang Y M, Chen H, He C L, Wang Q. Nitrogen starvation induced oxidative stress in an oil-producing green alga Chlorella sorokiniana C3. PLoS One, 2013, 8(7): e69225

承担项目：

1. 国家重点研发计划“合成生物学”重点专项：微藻底盘细胞的理性设计与系统改造，2021-2026，经费总额1949万元，主持；

2. 国家基金面上项目：Slr1970负调控Synechocystis 6803强光胁迫响应的新机制，2022-2025，经费总额58万元，主持；

3. 河南省高校科技创新团队：光合成生物学，2022-2024，经费总额50万元，主持；

4. 国家重点研发计划“合成生物学”重点专项子课题，抗光氧化运行模块/基因线路的设计、组装和优化，2020-2025，152万元，主持；

5. 973计划课题，微藻用于炼油过程CO₂减排的工程基础， 2012-2017，256万元，主持；

6. 973计划课题，能源微藻优良藻种的遗传改造，2011-2015，50万元，主持；

7. 国家自然科学基金重大研究计划项目，水圈碳循环原驱动力——水体初级生产力的原位无损分析方法的建立与应用，2019-2021，直接经费80万元，主持；

8. 国家自然科学基金面上项目，Synechocystis PCC 6803 缺铁诱导蛋白IsiA相互作用网络的构建及其功能研究，2013-2016，80万元，主持；

9. 国家自然科学基金面上项目，蓝细菌Synechocystis sp. PCC 6803 非编码反义RNA ThfR的功能及其调控机制研究，2018-2021，直接经费65万元，主持；

10. 科技部设备研制项目，水生态系统活力分析仪，2018-2019，296 万元，主持；

11. 湖北省自然科学基金重点项目，能源微藻用于去除工业烟气中氮氧化物(NOx)的研究，2013-2015，10万元，主持；

12. 湖北省自然科学基金创新群体项目，微藻固炭脱硝机理及高附加值产物的提取工艺，2017-2020，50万元，参加；

13. 中国科学院STS项目，微藻中亚麻酸的提取及富集技术，2016-2017，42万元，参加；

14. 特色所项目，梁子湖藻类研发基地试验平台建设，2015-2018，31万元，参加；

15. 创新领域前沿项目，基因工程制备微藻生物柴油关键技术的研究，2010-2012，100万元，主持；

16. 中科院创新领域前沿项目，中国科学院“百人计划”，2011-2013 ，260万元，主持；

17. 企业委托，炼厂烟气高耐受性微藻选育与培养工艺的研究，2013-2014，100万元，主持

18. 企业委托，“渔光一体”系列研究-草鱼养殖，养殖模式，理化因子，2015-2016，40万元，主持；

19. 企业委托，产油微藻发酵培养工艺及藻油提取工艺的研究，2017，10万元，主持