苗雨晨

职称：教授

联系电话：86-371-23897139(O)

传 真：86-371-23881387

E-mail：miaoych@henu.edu.cn

研究方向：植物逆境生理生化

团队成员：贾昆鹏，郭敬功，李坤

课题组博士研究生：2016级：杨勇；2018级：郭玉涛；2019级：贾江涛；2020级：张艳齐；2021级：邵露营；2022级：薛树娟

课题组硕士研究生：2020级：蒲梦洋，赵旭龙，梁小菡，乔璇，刘玉悦，张红玉，韩霄萌，朱志娟，王玉杰，施文倩；2021级：张钰，李瑾，徐世灿，柯丹平，程珂，徐坤，王哲，胡理群，任思璐，曹佳丹，邹玲敏，袁明慧，贾星雨；2022级：曹露露，何怡，窦云枫，翟亚辉，李航，张程，张璇，王欣逸，潘俞佩，种银行，张华敏，孙海玉

毕业研究生：

博士：2014级：郭敬功；2017级：李海鹏

硕士：2011级：唐景亮；2012级：卢延克，李瑞，宋洁琼；2013级：陈明杨，韩霜，王艺达；2014级：毕宝弟，郭明慧，王瑾；2015级：王红，邵梦莹；2016级：许锐，贾倩云；2017级：王亚平，孙露，谢文飞；2018级：孙亚如，田再垄；2019级：田红涛，张衡，高书文，付炜炜，杜静怡，张明慧

苗雨晨，博士，博士生导师，二级教授。

1994和2002年分别获河南大学学士和硕士学位，2005年于中国农业大学获博士学位。2008.12-2011.11在美国能源部布鲁克海文（Brookhaven）国家实验室从事博士后研究。入选“国家百千万人才工程”和“国家有突出贡献中青年专家”（2019年），享受国务院特殊津贴专家（2020）；先后被授予河南省学术技术带头人（2008）、第九批河南省优秀专家、中原千人计划基础研究领军人才（2018）、河南省高层次人才（B类）（2020年）；被聘为河南省特聘教授（2014）、河南省植物学会第八届理事会副理事长。组建了“水分胁迫与植物次生代谢调控”河南省高校科技创新团队，现为河南省作物逆境多组学国际联合实验室主任。

主要研究内容：

1、植物氧化还原信号转导的分子机制

围绕植物逆境生物学这一前沿领域，系统探讨了植物应答干旱胁迫的细胞及分子机理，确立了H₂O₂是ABA信号转导途径中新的信号分子，发现拟南芥谷胱甘肽还原酶（GPX3）具有清除和感受H₂O₂的双重功能。通过系统的遗传分析，结合基因组学和蛋白质组学，发现GPX7响应强光，通过与HCF244相互作用，参与维持光合反应中心组分的稳定性，从而调控拟南芥应答强光胁迫的分子机制。

2、植物次生代谢调控与逆境胁迫应答

次生代谢是植物长期适应环境变化而产生的，在植物生长发育与环境适应中起着重要作用。以模式植物和棉花为材料，着重以下几方面的研究：（1）开展苯丙烷类代谢类物质代谢和环境胁迫的关系，主要代谢物质和逆境胁迫信号转导的相互交联（cross-talk）。（2）利用基因组学、生物化学及遗传学手段阐明苯丙烷类和类胡萝卜素等次生代谢物质在逆境反应中的功能、作用对象及机制。

主持的研究项目

1. 国家自然科学基金（NO. 31770300），研究期限：2018.1-2021.12

2. 国家自然科学基金（NO. 31370332），研究期限：2014.1-2017.12

3. 国家自然科学基金（NO. 30770170），研究期限：2008.1-2010.12

4. 国家重点研发计划（NO. 2018YFD0100304），研究期限：2018.6-2020.12

5. 国家重点研发计划（NO. 2016YFD0101006），研究期限：2016.7-2020.12

6. 河南省高校科技创新团队（18IRTSTHN023），研究期限：2018.1-2019.12

7. 河南省科技创新杰出人才基金（NO. 144200510017），研究期限：2014.1-2016.12

8. 教育部高等学校博士学科点专项科研基金（博导类）（20134103110001），研究期限：2014.1-2016.12

主要论著目录（#为共同一作，*为通讯作者）：

1. Tian H, Watanabe Y, Nguyen KH, Tran CD, Abdelrahman M, Liang X, Xu K, Sepulveda C, Mostofa MG, Van Ha C, Nelson DC, Mochida K, Tian C, Tanaka M, Seki M, Miao Y, Tran LP, Li W. KARRIKIN UPREGULATED F-BOX 1 negatively regulates drought tolerance in Arabidopsis. Plant Physiology. 2022 Nov 28; 190(4): 2671-2687. DOI: 10.1093/plphys/kiac336.

2. Ke D#, Guo J#, Li K#, Wang Y, Han X, Fu W, Miao Y, Jia K. Carotenoid-derived bioactive metabolites shape plant root architecture to adapt to the rhizospheric environments. Frontiers in Plant Science, 2022 Otc 26; 13: 986414. DOI: 10.3389/fpls.2022.986414.

3. Huang P, Lu M, Li X, Sun H, Cheng Z, Miao Y, Fu Y*, Zhang X*. An efficient Agrobacterium rhizogenes-mediated hairy root transformation method in a soybean root biology study. International Journal of Molecular Sciences. 2022 Oct 14; 23(20): 12261. DOI: 10.3390/ijms232012261.

4. Feng Z, Liang X, Tian H, Watanabe Y, Nguyen KH, Tran CD, Abdelrahman M, Xu K, Mostofa MG, Van Ha C, Mochida K, Tian C, Tanaka M, Seki M, Liang Z, Miao Y*, Tran LP*, Li W*. SUPPRESSOR of MAX2 1 (SMAX1) and SMAX1-LIKE2 (SMXL2) negatively regulate drought resistance in Arabidopsis thaliana. Plant Cell Physiol. 2022 Jun 10:pcac080. DOI: 10.1093/pcp/pcac080.

5. Li H#, Zhang S#, Zhao Y#, Zhao X, Xie W, Guo Y, Wang Y, Li K, Guo J, Zhu QH, Zhang X, Jia K-P*, Miao Y*. Identification and characterization of cinnamyl alcohol dehydrogenase encoding genes involved in lignin biosynthesis and resistance to verticillium dahliae in upland cotton (Gossypium hirsutum L). Frontiers in Plant Science, 2022 Apr 28; 13: 840397. DOI: 10.3389/fpls.2022.840397.

6. Li W#, Sun Y#, Li K#, Tian H, Jia J, Zhang H, Wang Y, Wang H, Bi B, Guo J, Tran L-S P, Miao Y*. Sinapate esters mediate UV-B-induced stomatal closure by regulating nitric oxide, hydrogen peroxide, and malate accumulation in Arabidopsis thaliana. Plant and Cell Physiology, 2022 Apr 27: pcac059. DOI: 10.1093/pcp/pcac059.

7. Yang F, Miao Y, Liu Y, Botella Jose R, Li W, Li K, Song C-P*. Function of protein kinases in leaf senescence of plants. Frontiers in Plant Science, 2022 Apr 25, 13: 864215. DOI: 10.3389/fpls.2022.864215.

8. Qin H, Pandey BK, Li Y, Huang G, Wang J, Quan R, Zhou J, Zhou Y, Miao Y, Zhang D, Bennett MJ, Huang R. Orchestration of ethylene and gibberellin signals determines primary root elongation in rice. The Plant Cell. 2022 Mar 29; 34(4): 1273-1288. DOI: 10.1093/plcell/koac008.

9. Li K#, Jia Q#, Guo J#, Zhu Z, Shao M, Wang J, Dai J, Guo M, Li R, Song J, Yang F, Du J, Jose RB, Song C-P*, Miao Y*. The high chlorophyll fluorescence 244 (HCF244) is potentially involved in glutathione peroxidase 7-regulated high light stress in Arabidopsis thaliana. Environmental and Experimental Botany, 2022 Mar; 195(19): 104767. DOI: 10.1016/j.envexpbot.2021.104767.

10. Dong C#, Qu G#, Guo JG#, Wei F, Gao SW, Sun ZT, Jin LF, Sun XW, Rochaix JD, Miao Y*, Wang R*. Rational design of geranylgeranyl diphosphate synthase enhances carotenoid production and improves photosynthetic efficiency in Nicotiana tabacum. Science Bulletin, 2022 Feb 15; 67(3): 315-327. DOI: 10.1016/j.scib.2021.07.003.

11. Xu K, Zhang XM, Chen H, Zhang C, Zhu J, Cheng Z, Huang P, Zhou X, Miao Y, Feng X, Fu YF. Fine-tuning florigen increases field yield through improving photosynthesis in soybean. Frontiers in Plant Science. 2021 Aug 16; 12: 710754. DOI: 10.3389/fpls.2021.710754.

12. Wang X#, Miao Y#, Cai Y, Sun G, Jia Y, Song S, Pan Z, Zhang Y, Wang L, Fu G, Gao Q, Ji G, Wang P, Chen B, Peng Z, Zhang X, Wang X, Ding Y, Hu D, Geng X, Wang L, Pang B, Gong W*, He S*, Du X*. Large-fragment insertion activates gene GaFZ (Ga08G0121) and is associated with the fuzz and trichome reduction in cotton (Gossypium arboreum). Plant Biotechnology Journal, 2021 Jun; 19(6): 1110-1124. DOI: 10.1111/pbi.13532.

13. Zhang S, Guo Y, Zhang Y, Guo J, Li K, Fu W, Jia Z, Li W, Tran LP, Jia KP*, Miao Y*. Genome-wide identification, characterization and expression profiles of the CCD gene family in Gossypium species. 3 Biotech, 2021 May; 11(5): 249. DOI: 10.1007/s13205-021-02805-9.

14. Zhao B, Zhang S, Yang W, Li B, Lan C, Zhang J, Yuan L, Wang Y, Xie Q, Han J, Mur LAJ, Hao X, Roberts JA, Miao Y, Yu K, Zhang X. Multi-omic dissection of the drought resistance traits of soybean landrace LX. Plant, Cell and Environment, 2021 May; 44(5): 1379-1398. DOI: 10.1111/pce.14025.

15. Ji G, Liang C, Cai Y, Pan Z, Meng Z, Li Y, Jia Y, Miao Y, Pei X, Gong W, Wang X, Gao Q, Peng Z, Wang L, Sun J, Geng X, Wang P, Chen B, Wang P, Zhu T, He S, Zhang R, Du X. A copy number variant at the HPDA-D12 locus confers compact plant architecture in cotton. New Phytologist, 2021 Feb; 229(4): 2091-2103. DOI: 10.1111/nph.17059.

16. Dong W, Zhu Y, Chang H, Wang C, Yang J, Shi J, Gao J, Yang W, Lan L, Wang Y, Zhang X, Dai H, Miao Y, Xu L, He Z, Song C, Wu S, Wang D, Yu N, Wang E. An SHR-SCR module specifies legume cortical cell fate to enable nodulation. Nature, 2021 Jan; 589(7843): 586-590. DOI: 10.1038/s41586-020-3016-z.

17. Li W, Gupta A, Tian H, Nguyen KH, Tran CD, Watanabe Y, Tian C, Li K, Yang Y, Guo J, Luo Y, Miao Y*, Tran L-S P*. Different strategies of strigolactone and karrikin signals in regulating the resistance of Arabidopsis thaliana to water-deficit stress. Plant Signaling & Behavior, 2020 Sep 1; 15(9): 1789321. DOI: 10.1080/15592324.2020.1789321.

18. Cheng Z, Zhang X, Huang P, Huang G, Zhu J, Chen F, Miao Y, Liu L, Fu YF, Wang X. Nup96 and HOS1 are mutually stabilized and gate CONSTANS protein level, conferring long-day photoperiodic flowering regulation in Arabidopsis. The Plant Cell. 2020 Feb; 32(2): 374-391. DOI: 10.1105/tpc.19.00661.

19. Wang J, Qin H, Zhou S, Wei P, Zhang H, Zhou Y, Miao Y, Huang R. The ubiquitin-binding protein OsDSK2a mediates seedling growth and salt responses by regulating gibberellin metabolism in rice. The Plant Cell. 2020 Feb; 32(2): 414-428. DOI: 10.1105/tpc.19.00593.

20. Zhang S, Tian Z, Li H, Guo Y, Zhang Y, Zhang X*, Miao Y*. Genome-wide analysis and characterization of F-box gene family in Gossypium hirsutum L. BMC Genomics, 2019 Dec 19; 20: 993. DOI: 10.1186/s12864-019-6280-2.

21. Zhang S, Cai Y, Guo J, Li K, Peng R, Liu F, Miao Y*, Zhang X*. Genotyping-by-sequencing (GBS) of Gossypium hirsutum race accessions uncovers novel patterns of genetic structure and domestication footprints. Evolutionary Bioinformatics, 2019 Nov 20; 15: 1176934319889948. DOI: 10.1177/1176934319889948.

22. Dai P^#, Miao Y^#, He S, Pan Z, Jia Y, Cai Y, Sun J, Wang L, Pang B, Wang M, Du X*. Identifying favorable alleles for improving key agronomic traits in upland cotton. BMC Plant Biology, 2019 Apr 11; 19(1): 138. DOI: 10.1186/s12870-019-1725-y.

23. Li H^#, Li K^#, Guo Y, Guo J, Miao K, Botella JR, Song C-P, Miao Y*. A transient transformation system for gene characterization in upland cotton (Gossypium hirsutum). Plant Methods, 2018 Jun 22; 14: 50. DOI: 10.1186/s13007-018-0319-2.

24. Guo J^#, Li K^#, Jin L, Xu R, Miao K, Yang F, Qi C, Zhang L, Botella JR, Wang R*, Miao Y*. A simple and cost-effective method for screening of CRISPR/Cas9-induced homozygous/biallelic mutants. Plant Methods, 2018 May 29; 14: 40. DOI: 10.1186/s13007-018-0305-8.

25. Bi B, Tang J, Han S, Guo J, Miao Y*. Sinapic acid or its derivatives interfere with abscisic acid homeostasis during Arabidopsis thaliana seed germination. BMC Plant Biology, 2017 Jun 6; 17(1): 99. DOI 10.1186/s12870-017-1048-9.

26. Chen M, Li K, Li H, Song C-P*, Miao Y*. The glutathione peroxidase gene family in Gossypium hirsutum: genome-wide identification, classification, gene expression and functional analysis. Scientific Reports, 2017 Mar 16; 7, 44743. DOI: 10.1038/srep44743.

27. Li K#, Yang F#, Zhang G, Song S, Li Y, Ren D, Miao Y*, Song C-P*. AIK1, A mitogen-activated protein kinase, modulates abscisic acid responses through the MKK5-MPK6 kinase cascade. Plant Physiology, 2017 Feb; 173: 1391-1408. DOI: 10.1104/pp.16.01386.

28. Li K, Du Y, Miao Y*. Future challenges in understanding ROS in plant responses to abiotic stress. Science China Life Sciences, 2016 Dec; 59(12): 1343-1344. DOI: 10.1007/s11427-016-0362-7.

29. Song Y, Xiang F, Zhang G, Miao Y, Miao C, Song C-P*. Abscisic acid as an internal integrator of multiple physiological processes modulates leaf senescence onset in Arabidopsis thaliana. Frontiers in Plant Science, 2016 Feb 19; 7: 181. DOI: 10.3389/fpls.2016.00181.

30. Lei KJ, Lin YM, Ren J, Bai L, Miao Y, An GY, Song C-P*. Modulation of the phosphate-deficient responses by microRNA156 and its targeted SQUAMOSA PROMOTER BINDING PROTEIN-LIKE 3 in Arabidopsis. Plant & Cell Physiology, 2016 Jan; 57(1): 192-203. DOI: 10.1093/pcp/pcv197.

31. Zhang XL, Zhao XL, Li B, Xia J, Miao Y*. SRO1 regulates heavy metal mercury stress response in Arabidopsis thaliana. Chinese. Science. Bulletin, 2014 Jul 23; 59 (25): 3134-3141. DOI: 10.1007/s11434-014-0356-9.

32. Bai L, Ma X, Zhang G, Song S, Zhou Y, Gao L, Miao Y, Song C-P*. A receptor-like kinase mediates ammonium homeostasis and is important for the polar growth of root hairs in Arabidopsis. The Plant Cell, 2014 Apr; 26: 1497-1511. DOI: 10.1105/tpc.114.124586.

33. Song Y, Miao Y, Song C-P*. Behind the scenes: the roles of reactive oxygen species in guard cells. New Phytologist, 2014 Mar; 201(4): 1121-1140. DOI: 10.1111/nph.12565.

34. Wang PC, Du YY, Zhao XL, Miao Y, and Song C-P*. The MPK6-ERF6-ROSE7/GCC-box complex modulates oxidative gene transcription and the oxidative response in Arabidopsis thaliana. Plant Physiology, 2013 Mar; 161: 1392-1408. DOI: 10.1104/pp.112.210724.

35. Zhang KW, Bhuiya MW, Pazo JR, Miao Y, Kim H, Ralph J, and Liu C-J*. An engineered monolignol 4-O-methyltransferase (MOMT4) represses lignin polymerization and confers novel metabolic capability in Arabidopsis. The Plant Cell, 2012 Jul; 24(7): 3135-3152. DOI: 10.1105/tpc.112.101287.

36. Liu C-J*, Miao Y, Zhang KW. Sequestration and transport of lignin monomeric precursors. Molecules, 2011 Jan 18; 16: 710-727. DOI: 10.3390/molecules16010710.

37. Miao Y, Liu C-J*. ATP-binding cassette-like transporters are involved in the transport of lignin precursors across plasma and vacuolar membranes. Proc. Natl. Acad. Sci. USA., 2010 Dec 28; 107(52): 22728-22733. DOI: 10.1073/pnas.1007747108.

38. Miao Y, Guo JG, Liu ET, Li K, Dai J, Wang PC, Chen J, Song C-P*. Osmotic stress-regulated the expression of glutathione peroxidase 3 in Arabidopsis. Chinese Science Bulletin, 2007 Nov; 52(1): 127-130. DOI: 10.1007/s11434-007-0021-7.

39. Miao Y, Lv D, Wang P, Wang X-C, Chen J, Miao C, Song C-P*. An Arabidopsis glutathione peroxidase functions as both a redox-transducer and a scavenger in ABA and drought stress responses. The Plant Cell, 2006 Oct; 18: 2749-2766. DOI: 10.1105/tpc.106.044230.

40. Miao Y, Xia JC, Li BZ, Zhou Y, Song CP*. The Arabidopsis DOS1 as a common molecular switch mediates the H₂O₂ and drought stress signaling and confers heavy metal mercury tolerance. Cell Biol. Int., 2005; 29: S6.

41. Zhang X, Miao Y, An GY, Zhou Y, Sangguan ZP, Gao JF, Song C-P*. K⁺ channels inhibited by hydrogen peroxide mediate abscisic acid signaling in guard cells. Cell Research, 2001 Sep; 11: 195-202. DOI: 10.1038/sj.cr.7290086.

42. Miao, Y, Song, CP*, Dong, FC, Wang, XC. ABA-induced hydrogen peroxide generation in guard cells of Vicia faba. Acta Phytophysiol. Sin. 2000 Jan 1; 26(1): 53-58, (in Chinese).

专利授权情况：

1、国家发明专利“棉花谷胱甘肽过氧化物酶GhGPX8及应用”；专利号ZL 2017 1 0099270.6；授权公告日：2020年05月29日；发明人：苗雨晨；李坤；陈明杨；李海鹏；郭敬功；宋纯鹏。

2. 国家发明专利“芥子酸在种子萌发、根生长和幼苗发育方面的应用”；专利号ZL 2017 1 0295668.7，授权公告日：2020年06月02日，发明人：苗雨晨；李坤；郭敬功；唐景亮；毕宝弟；王红。

教学科研获奖情况：

1、“植物应答干旱胁迫的气孔调节机制”获2012年度国家自然科学奖二等奖（证书号：2012-Z-105-2-04-R03），第三完成人。

2、“提高植物水分利用效率的气孔调节机制”获2007年度教育部自然科学奖一等奖（证书号：2007-050），第三完成人。

3、“植物应答干旱胁迫的气孔和根系调控机制”获河南省创新争先奖牌，2017年，第二完成人。

4、“动物细胞培养”获国家虚拟仿真实验教学项目（证书编号：2018-2-0042），2018年，主持人。

5、“基于科教协作"菁英计划”的地方高校拔尖创新人才培养模式研究与实践”获河南省高等教育教学成果奖特等奖（证书编号：[2020]09126），2020年，第二完成人。

6、“提高植物养分水分高效利用根形态建成分子机制”获2020年度河南省自然科学奖一等奖（证书号：2020-Z-002-R07/10），第七完成人。

参编主要著作和教材情况：

1、宋纯鹏编著，编委：宋纯鹏、苗雨晨、王棚涛等。《气孔——土壤-植物-大气连续系统的枢纽》，科学出版社（ISBN 978-7-03-066670-3），2020，627000字。

2、张洪主编，苗雨晨、安国勇副主编。《细胞生物学实验数字课程》，高等教育出版社（ISBN 978-7-89510-662-8），2020。

3、宋纯鹏，王学路，周云等《植物生理学》译著，第五版，科学出版社，中国，2015，参译。

讲授课程：

1、细胞生物学（本科生）

2、生命科学研究进展和新生研讨课（本科生）

3、植物生物学前沿进展讲座（研究生）

4、生物文献阅读（研究生）

指导学生参加项目和竞赛：

1、大学生创新创业训练计划项目（国家级，项目编号，202110475047），GPX3关键半胱氨酸调控植物抗旱性分析，参与人：刘杨、杨柏语、韩悦、李瑞敏。

2、AtGPX3参与调控拟南芥抗旱性机制分析，参与人：杨柏语、张贝贝、林宇扬、刘杨、韩悦，全国大学生生命科学竞赛（2022，科学探究类）河南省赛区暨第五届河南省大学生生命科学竞赛省级三等奖。

联系方式：Email: miaoych@henu.edu.cn