郭思义

郭思义，男，博士，教授，博士生导师。2004年在河南大学获理学学士学位，2011年在中科院植物研究所获理学博士学位（硕博连读）。2011年11月至2012年5月，在中国科学院植物分子生理学重点实验室从事科研工作；2012年5月至2015年5月，在新加坡淡马锡生命科学研究院从事博士后研究。2015年5月，入选河南大学“黄河学者”特聘教授。2019年6月入选河南大学“攀登计划”特聘教授。

在Nature Communications、Plant and Cell Physiology、PLoS Genetics、Plant Physiology、Science、Plant Cell等国际著名期刊发表学术论文30余篇，SCI论文被引用次数达800多次,其中ESI全球高被引论文4篇；申请获得国家专利11项；主持国家自然基金面上项目两项、河南省高校创新团队一项、河南省教育厅重点项目一项，参与国家863重大研究项目1项及国家自然科学基金2项，参与新加坡NRF项目1项。

研究方向：

主要从事植物分子发育生物学方面的研究，包括单双子叶气孔发育、植物逆境生物学。

l学术任职

1）中国植物生理与植物分子生物学学会常务理事；

2）中国植物生理与植物分子生物学学会青年工作委员会副主任；

3）中国植物蛋白质组工作组理事

4）植物生理及分子生物学专业委员会委员

5）担任Frontiers in Plant Science编辑

6）担任New Phytologist审稿人

l学术荣誉与获奖情况

1）2017年获河南省创新争先奖

2）2020年获开封市优秀教师

l近5年学术会议口头报告情况

2017年11月，中国武汉，第三届全国植物细胞生物学大会，特邀报告；

2018年05月，中国开封，第三届全国植物逆境生物学大会，特邀报告。

代表性研究论文：

1.Siyi Guo, Yunyuan Xu, Huanhuan Liu, Zhiwei Mao, Cui Zhang, Yan Ma, Qirui Zhang, Zheng Meng, Kang Chong. The interaction between OsMADS57 and OsTB1 modulates rice tillering via DWARF14.Nature Commun, 2013; 4:1566. (Evaluated by Faculty of 1000)（ESI全球高被引论文）

2.Hao Liu¹,Siyi Guo¹,Minghua Lu, Yuzhang, Junhua Li, Wei Wang, Pengtao Wang, Junli Zhang, Zhubing Hu, Liangliang Li, Lingyu Si, Jie Zhang, Qi Qi, Xiangning Jiang, José Ramón Botella, Hua Wang & Chun-Peng Song. Biosynthesis of DHGA₁₂and its roles in Arabidopsis seedling establishment.Nature Commun, 2019; 10:1768.(¹Contribute equally to this work)（ESI全球高被引论文）

3.Hongliang Wang¹,Siyi Guo¹, Xin Qiao, Jianfei Guo, Zuliang Li, Yusen Zhou, Shenglong Bai, Zhiyong Gao, Daojie Wang, Pengcheng Wang David W. Galbraith and Chun-Peng Song. BZU2/ZmMUTE controls symmetrical division of guard mother cell and specifies neighbor cell fate in maize.PLoS Genet, 2019; 15(8): e1008377.

4.Wenjing Wang, Qingbin Chen, Jimmy R Botella andSiyi Guo. Beyond light: insights into the role of COP1 in plant hormonal signaling.Front Plant Sci,2019; 10:557.(通讯作者)

5.Siyi Guo,Shaojun Dai, Prashant K. Singh, Hongyan Wang, Yanan Wang, Jeanie L. H. Tan, Wanyi Wee, Toshiro Ito. A membrane-bound NAC-Like transcription factor OsNTL5 represses the flowering inOryza sativa.Front Plant Sci,2018; 9:555.(通讯作者)（ESI全球高被引论文）

6.Siyi Guo, Bo Sun, Liang-Sheng Looi, Yifeng Xu, Eng-Seng Gan, Jiangbo Huang, Toshiro Ito. Co-ordination of flower development through epigenetic regulation in two model species: rice and Arabidopsis.Plant and Cell Physiol, 2015; 56(5):830-842.

7.Huanhuan Liu¹,Siyi Guo¹, Yunyuan Xu, Chunhua Li, Zeyong Zhang, Dajian Zhang, Shujuan Xu, Cui Zhang, Kang Chong. OsmiR396d-regulated OsGRFs function in floral organogenesis in rice through binding to their targetsOsJMJ706andOsCR4.Plant Physiol,2014; 165:160-174.(¹Contribute equally to this work)

8.Yuebin Jia, Xiangpei Kong, Kongqin Hu, Mengqiang Cao, Jiajia Liu, Changle Ma,Siyi Guo, Xianzheng Yuan, Shan Zhao,Hélène S. Robert, Cuiling Li, Huiyu Tian, Zhaojun Ding. PIFs coordinate shade avoidance by inhibiting auxin repressor ARF18 and metabolic regulatorQQS.New Phytol, 2020; 228(2):609-621.

9.Xiangpei Kong, Chunlei Zhang, Huihui Zheng, Min Sun, Feng Zhang, Mengyue Zhang, Fuhao Cui, Dongping Lv, Lijing Liu,Siyi Guo, Youming Zhang, Xianzheng Yuan, Shan Zhao, Huiyu Tian, Zhaojun Ding. Antagonistic Interaction between Auxin and SA Signaling Pathways Regulates Bacterial Infection through Lateral Root in Arabidopsis.Cell Rep, 2020; 32(8):108060.

10.Xiaohui Qin, Zhikun Duan, Yuan Zheng, Wen-Cheng Liu, Siyi Guo,José Ramón Botella, Chun-Peng Song. ABC1K10a, an atypical kinase, functions in plant salt stress tolerance. BMC Plant Biol. 2020; 20:270.

11.Yang Liu, Jiameng Xu, Siyi Guo, Xianzheng Yuan, Shan Zhao, Huiyu Tian, Shaojun Dai, Xiangpei Kong, Zhaojun Ding. AtHB7/12 Regulate Root Growth in Response to Aluminum Stress.Int J Mol Sci, 2020; 21(11):4080.

12.Yamei Wang, Wenwen Liu, Xinwei Wang, Ruijuan Yang, Zhenying Wu, Han Wang, Lei Wang, Zhubing Hu, Siyi Guo, Hailing Zhang, Jinxing Lin, Chunxiang Fu. MiR156 regulates anthocyanin biosynthesis through SPL targets and other microRNAs in poplar.Hortic Res, 2020; 7:118.

13.Hailing Zhang, Yingping Cao, Huan Zhang, Yue Yu, Chuanen Zhou, Wenwen Liu, Ruifen Zhu, Chen Shang, Jikai Li, Zhongbao Shen, Siyi Guo, Zhubing Hu, Chunxiang Fu, Dequan Sun. Efficient Generation of CRISPR/Cas9-Mediated Homozygous/Biallelic Medicago truncatula Mutants Using a Hairy Root System.Front Plant Sci, 2020; 11:294.

14.Juanjuan Yu, Ying Li, Zhi Qin,Siyi Guo, Yongfang Li, Yuchen Miao, Chunpeng Song, Sixue Chen, Shaojun Dai. Plant Chloroplast Stress Response: Insights from Thiol Redox Proteomics.Antioxid Redox Signal, 2020; 33:35-37.

15.Yongxue Zhang, Yue Zhang, Juanjuan Yu, Heng Zhang, Liyue Wang, Sining Wang, Siyi Guo, Yuchen Miao, Sixue Chen, Ying Li, Shaojun Dai. NaCl-responsive ROS Scavenging and Energy Supply in Alkaligrass Callus Revealed From Proteomic Analysis.BMC Genom, 2019; 20(1):990.

16.Shanshan Li, Juanjuan Yu, Ying Li, Heng Zhang, Xuesong Bao, Jiayi Bian, Chenxi Xu, Xiaoli Wang, Xiaofeng Cai, Quanhua Wang, Pengcheng Wang,Siyi Guo, Yuchen Miao, Sixue Chen, Zhi Qin and Shaojun Dai. Heat-Responsive Proteomics of a Heat-Sensitive Spinach Variety.Int J Mol Sci, 2019; 20(16): 3872.

17.Wangdan Xiong, Zhenyi Wu, Yuchen Liu, Yu Li, Kunlong Su, Zetao Bai,Siyi Guo, Zhubing Hu, Zhiming Zhang, Yan Bao, Juan Sun, Guofeng Yang and Chunxiang Fu. Mutation of 4-coumarate: coenzyme A ligase 1 gene affects lignin biosynthesis and increases the cell wall digestibility in maize brown midrib5 mutants.Biotechnol Biofuels, 2019; 12:82.

18.Hong Cao¹,Siyi Guo¹, Yunyuan Xu, Kun Jiang, Alan M. Jones, Kang Chong. Reduced expression of a gene encoding a Golgi localized monosaccharide transporter (OsGMST1) confers hypersensitivity to salt in rice (Oryza sativa).J Exp Bot, 2011; 62:4595–4604. (¹Contribute equally to this work) (Evaluated by Faculty of 1000)

19.Bo Sun, Liang-Sheng Looi,Siyi Guo,Zemiao He, Eng-Seng Gan, Jiangbo Huang, Yifeng Xu, Wan-Yi Wee, Toshiro Ito. Timing mechanism dependent on cell division is invoked by polycomb eviction in plant stem cells.Science,2014; 343 (6170):1248559.

20.Yongyan Tang¹, Huanhuan Liu¹,Siyi Guo, Bo Wang, Zhitao Li, Kang Chong, Yunyuan Xu. OsmiR396d affects gibberellin and brassinosteroid signaling to regulate plant architecture in rice.Plant Physiol,2018; 176:946-959.(¹Contribute equally to this work)（ESI全球高被引论文）

21.Zeping Yin, Heng Zhang, Qi Zhao, Mi-Jeong Yoo, Ning Zhu, Jianlan Yu, Juanjuan Yu,Siyi Guo, Yuchen Miao, Sixue Chen, Zhi Qin, Shaojun Dai. Physiological and comparative proteomic analyses of saline-alkali NaHCO3-responses in leaves of halophyte Puccinellia tenuiflora. Plant and Soil, 2019; 437: 137-158.

22.Juanjuan Yu, Yongxue Zhang, Junming Liu, Lin Wang, Panpan Liu, Zepeng Yin,Siyi Guo, Jun Ma, Zhuang Lu, Tai Wang, Yimin She, Yuchen Miao, Ling Ma, Sixue Chen, Ying Li, Shaojun Dai. Proteomic discovery of H2O2 response in roots and functional characterization ofPutGLPgene from alkaligrass.Planta, 2018 Jul 23. doi: 10.1007/s00425-018-2940-8.

23.Huanhuan Liu, Yan Ma, Na Chen,Siyi Guo, Huili Liu, Xiaoyu Guo, Kang Chong, Yunyuan Xu. Overexpression of stress-inducible OsBURP16, the beta-subunit of polygalacturonase 1, decreases pectin contents and cell adhesion, and increases abiotic stress sensitivity in rice.Plant Cell Environ, 2014; 37: 1144–1158.

24.Qi Zhao, Wenxin Chen, Jiayi Bian, Hao Xie, Ying Li, Chenxi Xu, Jun Ma,Siyi Guo, Jiaying Chen, Xiaofeng Cai, Xiaoli Wang, Quanhua Wang, Yimin She, Sixue Chen, Zhiqiang Zhou and Shaojun Da. Proteomics and Phosphoproteomics of heat stress-responsive mechanisms in spinach.Fron Plant Sci,2018; 9:800.

25.Huijie Qi, Lihong Niu, Jie Zhang, Jian Chen, Shujie Wang, Jingjing Yang,Siyi Guo, Tom Lawson, Bingyang Shi, Chunpeng Song. Large-area gold nanohole arrays fabricated by one-step method for surface plasmon resonance biochemical sensing.Sci China Life Sci,2018; 10.1007/s11427-017-9270-x.

26.Yuanyuan Zhang, Beibei Li, Yunyuan Xu, Heng Li, Shanshan Li, Dajian Zhang, Zhiwei Mao,Siyi Guo, Chunhong Yang, Yuxiang Weng, Kang Chong.The cyclophilin CYP20-2 modulates the conformation of BRASSINAZOLE-RESISTANT1, which binds the promoter of FLOWERING LOCUS D to regulate flowering in Arabidopsis.Plant Cell,2013;25(7):2504-21.

27.Cui Zhang, Yunyuan Xu,Siyi Guo, Jiaying Zhu, Qing Huan, Lei Wang, Guanzheng Luo, Xiujie Wang and Kang Chong. Dynamics of Brassinosteroid Response Modulated by Negative Regulator LIC in Rice.PLoS Genetics,2012; 8 (4):e1002686.

28.Fei Li,Siyi Guo, Yuan Zhao, Dazhou Chen, Kang Chong, Yunyuan Xu. (2010). Overexpression of a homopeptide repeat-containing bHLH protein gene (OrbHLH001) from Dongxiang Wild Rice confers freezing and salt tolerance in transgenic Arabidopsis.Plant Cell Reports, 2010;29(9):977-986.

29.王宏亮,郭建飞,李祖亮,郭思义*.适于玉米基因图位克隆的SSR标记开发与应用.分子植物育种, 2017; 15(12):5000-5005.

30.王宏亮,郭思义,王棚涛,宋纯鹏.植物气孔发育机制研究进展.植物学报, 2018; 53(2):1-1.

申请获得专利：

1.种康、郭思义、徐云远。microRNA444a或其编码基因在调控水稻分蘖中的应用。授权公告日：2013.10.16，专利号：ZL201210141053.6

2.种康、郭思义、徐云远。OsMADS57蛋白或其编码基因在促进水稻分蘖中的应用。授权公告日：2014.03.26，专利号：ZL201210182988.9

3.种康、郭思义、徐云远。microRNA444a或其编码基因在调控水稻株高中的应用。授权公告日：2014.03.26，专利号：ZL201210141051.7

4.种康、郭思义、徐云远。OsMADS57蛋白或其编码基因在抑制水稻分蘖中的应用。授权公告日：2014.7.30，专利号：ZL 201210183051.3

5.种康、陈丽萍、马岩、郭思义、牛遇达、徐云远。microRNA444a或其编码基因在调节水稻耐盐性中的应用。授权公告日：2016. 05. 11，专利号：ZL 201310009657.X

6.种康、刘唤唤、郭思义、徐云远、赵原。OsGRF6蛋白在调控植物株高中的应用。授权公告日：2015. 03. 25，专利号：ZL 201210140837.7

7.种康、刘唤唤、郭思义。microRNA396d或其编码基因在调控水稻叶夹角中的应用。授权公告日：2014. 12. 31，专利号：ZL 201210142346.6

8.种康、刘唤唤、郭思义、徐云远。microRNA396d或其编码基因在调控水稻株高中的应用。授权公告日：2014. 12. 31，专利号：ZL 201210142354.0

9.种康、刘唤唤、郭思义、徐云远。microRNA396d或其编码基因在调控水稻开颖中的应用。授权公告日：2014. 12. 31，专利号：ZL 201210140986.3

主持或参加项目情况（按时间倒序排序）

1.国家自然科学基金项目：拟南芥泛素连接酶MAC3A/B与去泛素化酶UBP14协同调控器官大小（31970808），2020/01-2023/12,57万元，主持人。（在研）

2.国家自然科学基金项目：拟南芥AT hook家族基因（AHL5/9/11/12）维持茎顶端分生组织功能的分子机制（31671517），2017/01-2020/12，60万元，主持人。（已结题）

3.河南省高校科技创新团队支持计划：玉米水分高效利用的分子机制（21IRTSTHN019），2021/01-2023/12，50万，主持人。（在研）

4.河南省高等学校重点项目：玉米气孔发育突变体dos07的研究，2016/01-2017/12，3万元，主持人。（已结题）

5.河南大学“黄河学者”特聘教授启动基金项目：玉米气孔发育分子机制的研究，2015/05–2020/05，50万元，主持人。（已结题）

6.国家自然科学基金项目：miR444对水稻株高和耐低温性的调控，2011/01–2013/12，30万元，参与。（已结题）

7.国家自然科学基金项目：利用单子叶植物二穗短柄草研究新型miRNA耐低温的分子，2010/01–2012/12，30万元，参与。（已结题）

8.国家863重大项目：水稻株高等性状基因的克隆及功能鉴定，2006/12–2011/12，120万元，参与。（已结题）

讲授课程：

1.分子生物学（本科生）

2.植物发育生物学（硕、博士生）

联系电话：86-371-23881387

传真：86-371-23881387

E-mail：guosiyi@henu.edu.cn